Symbol Name ID |
Acvr2b
activin receptor IIB MGI:87912 |
! | Indicates phenotype varies with strain background. |
Darker colors indicate more annotations |
Human Phenotypes | Dextrocardia |
Situs inversus totalis |
Mesocardia |
Left atrial isomerism |
Right atrial isomerism |
Atrial septal defect |
Patent foramen ovale |
Common atrium |
Ventricular septal defect |
Atrioventricular canal defect |
Complete atrioventricular canal defect |
Unbalanced atrioventricular canal defect |
Subvalvular aortic stenosis |
Single ventricle |
Mitral atresia |
Double outlet right ventricle |
Transposition of the great arteries |
Dextrotransposition of the great arteries |
Cardiomegaly |
Hypoplastic left heart |
Right aortic arch |
Hypoplastic aortic arch |
Coarctation of aorta |
Pulmonary artery atresia |
Total anomalous pulmonary venous return |
Interrupted inferior vena cava with azygous continuation |
Bilateral superior vena cava |
Left superior vena cava draining to coronary sinus |
Patent ductus arteriosus |
Mitral stenosis |
Pulmonic stenosis |
Asplenia |
Ectopia of the spleen |
Polysplenia |
Disease(s) Associated with ACVR2B | ||||||||||||||||||||||||||||||||||
visceral heterotaxy |
Mouse Phenotypes | abnormal cardiac outflow tract development |
abnormal heart development |
abnormal direction of heart looping |
transposition of great arteries |
right atrial isomerism |
atrial septal defect |
abnormal heart position or orientation |
dextrocardia |
mesocardia |
ventricular septal defect |
|
Availability | Mouse Genotype | ||||||||||
Acvr2btm1Enl/Acvr2btm1Enl | ! | ! | ! | ||||||||
Acvr2btm1Spo/Acvr2btm1Spo | ! |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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